Tag: Robert Liston

Wellcome Book Prize Shortlist Event

Five of the six shortlisted authors (barring Dublin-based Mark O’Connell) were at the Wellcome Collection in London yesterday to share more about their books in mini-interviews with Lisa O’Kelly, the associate editor of the Observer. She called each author up onto the stage in turn for a five-minute chat about her work, and then brought them all up for a general conversation and audience questions. Clare and I found it a very interesting afternoon. Here’s some context that I gleaned about the five books and their writers.

Ayobami Adebayo says sickle cell anemia is a massive public health problem in Nigeria, as brought home to her when some friends died of complications of sickle cell. She herself was tested for the gene and learned that she is a carrier, so her children would have a 25% chance of having the disease if her partner was also a carrier. Although life expectancy with the disease has improved to 45–50, a cure is still out of reach for most Nigerians because bone marrow/stem cell transplantation and anti-rejection drugs are so expensive. Compared to the 1980s, when her book opens, she believes polygamy is becoming less fashionable in Nigeria and people are becoming more open to other means of becoming parents, whether IVF or adoption. It’s a way of acknowledging, she says, that parenthood is “not just about biology.”

Sigrid Rausing started writing her book soon after her sister-in-law Eva’s body was found: just random paragraphs to make sense of what had happened. From there it became an investigation, a quest to find the nature of addiction. She thinks that as a society we still don’t quite understand what addiction is, and the medical research and public perception are very separate. In addition to nature and nurture, she thinks we should consider the influence of culture – as an anthropologist by training, she’s very interested in drug culture and how that drew in her brother, Hans. Although there have been many memoirs by ex-addicts, she can’t think of another one by a family member. Perhaps, she suggested, this is because the addict is seen as the ultimate victim. She referred to her book as a “collage,” a very apt description.

Kathryn Mannix spoke of how her grandmother, born in 1900, saw so much more death than we do nowadays: siblings, a child, and so on. Today, though, Mannix has encountered people in their sixties who are facing, with their parents, their very first deaths. Death is fairly “gentle” and “dull” if you’re not directly involved, she insists; she blames Hollywood and Eastenders for showing unusually dramatic deaths. She said once you understand what exactly people are afraid of about dying (e.g. hell, oblivion, pain, leaving their families behind) you can address their specific concerns and thereby “beat out the demon of terror and fear.” Mannix never intended to write a book, but someone heard her on the radio and invited her to do so. Luckily, from her medical school days onward, she’d been writing an A4 page about each of her most mind-boggling cases to get them out of her head and move on. That’s why, as O’Kelly put it, the characters in her 30 stories “leap off the page.”

Mannix, Adebayo, O’Kelly, Rausing, Wadman & Fitzharris

Lindsey Fitzharris called The Butchering Art “a love story between science and medicine” – it was the first time that the former (antisepsis) was applied to the latter. She initially thought Robert Liston was her man – he was so colorful, larger than life – but eventually found that the real story was with Joseph Lister, the quiet, persistent Quaker. (However, the book does open with Liston performing the first surgery under ether.) Fitzharris is also involved in the Order of the Good Death, author Caitlin Doughty’s initiative, and affirmed Mannix’s efforts to remove the taboo from talking about death. I think I heard correctly that she said there is a film of The Butchering Art in the works?! I’ll need to look into that some more.

Meredith Wadman started with a brief explanation of how immunization works and why the 1960s were ripe for vaccine research. This segment went really science-y, which I thought was a little unfortunate as it may have made listeners tune out and be less interested in her work than the others’. It was perhaps inevitable given her subject matter, but also a matter of the questions O’Kelly asked – with the others she focused more on stories and themes than on scientific facts. It was interesting to hear what Wadman has been working on recently: for the past 6–8 months, she’s been reporting for Science on sexual harassment in science. For her next book, though, she’s pondering the conflict between a congressman and a Centers for Disease Control scientist over funding into research that might lead to gun control.

 


The question time brought up the issues of medical misinformation online, the distrust people with chronic illnesses have of medical professionals, and euthanasia – Mannix rather dodged that one, stating that her book is about the natural dying process so that’s not really her area. (Though it does come up in a chapter of her book.) We also heard a bit about the projects up next for each author. Rausing’s next book will be a travel memoir about the Capetown drought, taking in apartheid and her husband’s family’s immigration. Adebayo is at work on a very nebulous novel “about people,” and possibly how privilege affects access to healthcare.

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One More Wellcome Longlist Review & Shortlist Predictions

Tomorrow the six titles on the Wellcome Book Prize shortlist will be revealed. I’ve managed to read one more from the longlist since my last batch.

 

The Butchering Art: Joseph Lister’s Quest to Transform the Grisly World of Victorian Medicine by Lindsey Fitzharris

Surgery was a gory business with a notably high fatality rate well into the nineteenth century. Surgeons had the fastest hands in the West, but their victims were still guaranteed at least a few minutes of utter agony as they had a limb amputated or a tumor removed, and the danger wasn’t over after they were sewn up either: most patients soon died from hospital infections. The development of anesthetics and antiseptic techniques helped to change all that.

Fitzharris opens with the vivid and rather gruesome scene of a mid-thigh amputation performed by Robert Liston at University College Hospital in London in 1846. This surgery was different, though: it only took 28 seconds, but the patient felt nothing thanks to the ether he had been administered. He woke up a few minutes later asking when the procedure would begin. In the audience that day was Joseph Lister, who would become one of Britain’s most admired surgeons.

Lister came from a Quaker family and, after being educated at University College London, started his career in Edinburgh. Different to many medical professionals of the time, he was fascinated by microscopy and determined to find out what caused deadly infections. Carbolic acid and catgut ligatures were two of Lister’s main innovations that helped to fight infection. In fact, whether we realize it or not, his legacy is forever associated with antiseptics: Listerine mouthwash (invented in 1879) is named after him, and the Johnson brothers of Johnson & Johnson fame started their business mass-producing sterile surgical dressings after attending one of Lister’s lectures.

My interest tailed off a bit after the first third, as the book starts going into more depth about Lister’s work and personal life: he married his boss’s daughter and moved from Edinburgh to Glasgow and then back to London. However, the best is yet to come: the accounts of the surgeries he performed on his sister (a mastectomy that bought her three more years of life) and Queen Victoria (removing an orange-sized abscess from under her arm) are terrific. The chapter on treating the queen in secret at Balmoral Castle in 1871 was my overall favorite.

It probably wasn’t the best idea to start this book over my lunch one day!

I was that kid who loved going to Civil War battlefields and medical museums and looking at all the different surgical saws and bullet fragments in museum cases, so I reveled in the gory details here but was not as interested in the biographical material. Do be sure you have a strong stomach before you try reading the prologue over a meal. This is a comparable read to The Remedy, about the search for a cure to tuberculosis.

My rating:

 


Shortlist Predictions

Now, I’ve still only read half of the longlisted titles so far, so it’s hard to make any solid guesses. However, the below fall somewhere between wishes and informed predictions:

  1. In Pursuit of Memory by Joseph Jebelli: A definitive treatment of an epidemic of our time, Alzheimer’s disease. The neuroscientist author achieves the right balance between history and research on the one hand and personal stories readers can relate to on the other.
  2. The White Book by Han Kang: The only fiction title from the longlist that I haven’t read at least part of. This is also on this year’s Man Booker International Prize longlist and has been well received. From what I can tell, the health theme seems stronger than that of Stay with Me or Midwinter Break, and it would also be nice for one title in translation to make the shortlist.
  3. With the End in Mind by Kathryn Mannix: As I said in my review last week, this is an excellent all-round guide to preparation for death, based around touching patient stories plus the author’s experience in palliative care and CBT. Practical, compassionate and helpful.
  4. I Am, I Am, I Am by Maggie O’Farrell: For me, this book stands out as the one that most clearly illuminates the effects of illness, medical treatment, and other threats to life and limb in the course of an ordinary existence. I’d be very happy to see it win the whole thing.
  5. EITHER The Butchering Art by Lindsey Fitzharris OR The Vaccine Race by Meredith Wadman: I reckon one history of science title deserves to be on there; I think Wadman might have the slight edge.
  6. EITHER To Be a Machine by Mark O’Connell OR Behave by Robert Sapolsky: The Wellcome Prize loves big books investigating human tendencies and possibilities. I find the thought of either of these daunting, but I know they would also be illuminating. I’d prefer to read the O’Connell, but I’d give the edge to Sapolsky.

Any predictions of your own to make?